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Depression[ edit ] Bupropion is one of the most widely prescribed antidepressants, and the available evidence indicates that it is effective in clinical depression [17] — as effective as several other widely prescribed drugs, including fluoxetine 150mg and paroxetine Paxilzyban lp 150mg, [18] although trends favoring the efficacy of escitalopram Lexaprosertraline Zoloft and venlafaxine Effexor over bupropion have zyban observed.
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A typical bupropion treatment course lasts up to twelve weeks, with people halting the use of tobacco about ten days into the course, zyban lp 150mg. Bupropion approximately doubles the chance of quitting smoking successfully. Its effect may also be "considerably less than of the approved agents Thus it may be 150mg for the 150mg to recommend a trial of behavior therapy at this point, before moving to these zyban agents, zyban lp 150mg.
Food and Drug Administration. There have also been a few studies suggesting that bupropion can improve sexual function in women who zyban not depressed, if they have hypoactive sexual desire disorder HSDD. There has been controversy about whether it is useful to add an antidepressant such as bupropion to a mood stabilizer in people with bipolar depressionbut recent reviews have concluded that bupropion in this situation does no significant harm and may sometimes give significant benefit.
It should be avoided in individuals who are also taking monoamine oxidase inhibitors MAOIs.
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When switching from MAOIs to bupropion, it is important to include a washout period of about two weeks between the medications. List of side effects of bupropion Epileptic seizures are the most important adverse effect of bupropion, zyban lp 150mg.
A 150mg incidence of seizures was zyban for the temporary withdrawal of the drug from the market between and The risk of seizure 150mg strongly dose-dependent, but also dependent on the preparation, zyban lp 150mg.
The sustained-release preparation is associated with a seizure incidence of 0. Approximatelyzyban lp 150mg, people were treated with bupropion for smoking cessation during that period.
The agency concluded that "in the majority of cases the individual's underlying condition may provide an alternative explanation. This warning is based zyban a statistical analysis conducted by the FDA which found a 2-fold increase in suicidal thought and behavior in children and adolescents, and 1. Considered in isolation, bupropion was not statistically different from placebo.
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According to a Cochrane reviewzyban lp 150mg, while there is an association with suicide it 150mg unclear if bupropion was the cause. Some people, according to the advisory, have become depressed or have had their 150mg worsen, have had thoughts about 150mg or dying, or have attempted suicide. In most cases these symptoms can be reduced or eliminated by reducing the dose, ceasing treatment or adding antipsychotic medication.
When bupropion was one of several kinds of pills taken in an overdose, fever, muscle rigidity, muscle damage, hypertension or hypotension, stupor, coma, and zyban failure have been reported. While most people recover, some people have died, and before they died zyban multiple uncontrolled seizures and heart attacks. The expected result is the increase of bupropion and decrease of hydroxybupropion blood concentration.
The reverse effect decrease of bupropion and increase of hydroxybupropion can be expected with CYP2B6 inducerssuch as carbamazepineclotrimazolezyban lp 150mg, rifampicinritonavirSt John's wortzyban lp 150mg, phenobarbitalphenytoin and others. Caution should be observed when combining bupropion with a monoamine oxidase inhibitor MAOIas it may zyban in hypertensive crisis.