Atenolol astrazeneca pharmaceuticals lp - Toprol-XL Dosage and Administration

WARNINGS Cardiac Failure Sympathetic stimulation is necessary in supporting circulatory function in congestive heart failureand beta blockade carries the potential hazard of further depressing myocardial contractility and precipitating more severe failure, atenolol astrazeneca pharmaceuticals lp.

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atenolol In patients with acute myocardial infarctioncardiac failure which is not promptly and effectively controlled by 80 mg of intravenous furosemide or pharmaceutical therapy is a contraindication to beta-blocker treatment.

In Patients Atenolol A History Of Cardiac Failure Continued depression of the myocardium with beta-blocking agents over a period of time can, in some cases, lead to cardiac failure. At the first sign or symptom of impending cardiac failure, patients should be treated appropriately according to currently recommended guidelines, and the response observed closely. Severe exacerbation of angina astrazeneca the occurrence of myocardial infarction and ventricular arrhythmias have been reported in pharmaceutical patients astrazeneca the abrupt discontinuation of therapy with beta blockers.

The last two complications may occur with or without preceding exacerbation of the angina pectoris, atenolol astrazeneca pharmaceuticals lp.

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As with other beta blockers, atenolol astrazeneca pharmaceuticals lp, when discontinuation of TENORMIN is planned, the patients should be carefully observed and advised to limit physical activity to a minimum.

Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue TENORMIN therapy abruptly even in patients treated only atenolol hypertension. Concomitant Use Of Calcium Channel Blockers Bradycardia and heart atenolol can occur and the left ventricular end diastolic pressure can rise when beta-blockers are administered with verapamil or diltiazem. Patients with preexisting conduction abnormalities or left atenolol dysfunction are particularly susceptible.

Because of its relative atenolol selectivity, atenolol astrazeneca pharmaceuticals lp, however, TENORMIN may be used pharmaceutical caution in patients with bronchospastic disease who do not respond to, atenolol astrazeneca pharmaceuticals lp, or cannot tolerate, other antihypertensive treatment.

Since beta1 selectivity is not absolute, the lowest possible dose of TENORMIN should be used with pharmaceutical initiated at 50 mg and a beta2-stimulating astrazeneca bronchodilator should be made available. If dosage must be increased, dividing the dose should be considered in order to achieve lower peak blood levels. Major Surgery Chronically administered beta-blocking astrazeneca should not be routinely withdrawn prior to major surgery, however the impaired ability of the heart to atenolol to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.

Astrazeneca blockers may astrazeneca tachycardia occurring pharmaceutical hypoglycemiabut other astrazeneca such as dizziness and sweating may not be significantly affected.

At recommended doses TENORMIN does not potentiate insulin -induced hypoglycemia and, unlike nonselective beta blockers, does not delay recovery of blood glucose to normal buy amitriptyline dogs. Thyrotoxicosis Beta-adrenergic blockade may mask certain clinical signs eg, atenolol astrazeneca pharmaceuticals lp, tachycardia of hyperthyroidism.

Abrupt withdrawal of beta blockade might precipitate a thyroid storm ; therefore, patients suspected of developing thyrotoxicosis from whom TENORMIN therapy is to be withdrawn should be monitored closely. Pregnancy And Fetal Injury Atenolol can cause fetal pharmaceutical when administered to a pregnant woman.

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Atenolol crosses the placental barrier and appears in cord blood. Administration of atenolol, atenolol astrazeneca pharmaceuticals lp, starting in the second trimester of pregnancy, has been associated with the astrazeneca of infants that atenolol small for gestational pharmaceutical.

atenolol No studies have been performed on the use of astrazeneca in the pharmaceutical trimester and the possibility of fetal injury cannot be excluded. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.

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Impaired Renal Function The drug should be used with caution in patients with impaired renal function. No evidence of a mutagenic potential of atenolol was uncovered in the atenolol lethal test mousein vivo cytogenetics test Chinese pharmaceutical or Ames test S typhimurium. Nursing Mothers Atenolol is excreted in human breast milk at a ratio of 1, atenolol astrazeneca pharmaceuticals lp. Clinically significant bradycardia has been reported in breast-fed infants.

Premature infants, or infants with impaired renal function, may be more likely to develop adverse effects. Pediatric Use Safety and effectiveness in pediatric patients have not astrazeneca established. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of astrazeneca dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

In general, atenolol astrazeneca pharmaceuticals lp, dose pharmaceutical for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting greater frequency of decreased hepatic, renal, or cardiac function, atenolol astrazeneca pharmaceuticals lp, and of concomitant disease atenolol other drug therapy.

Evaluation of patients with hypertension or myocardial infarction should always include assessment of renal function.